Floris Lafeber (1961) is professor of ‘Experimental Rheumatology at the University Medical Centre Utrecht (UMC Utrecht; NL since 2009), manager of research of the dept. of Rheumatology & Clinical Immunology and head of its research laboratory (since 1992), manager research of the devision of Internal Medicine & Dermatology (since Feb 2016), and cofounder of ArthroSave BV.
He studied Biology at the Univ. of Nijmegen (NL; graduated Nov 1984), did his PhD at this Univ. in collaboration with the Univ. of Leiden (NL), with a visit of three months at the dept of Physiology, Univ. of Ottawa (Canada) (graduated April 1988). He is scientifically active in the field of ‘Regenerative Medicine and ‘Immunology.
Currently, his main interest is in novel treatments (joint distraction to treat end-stage knee osteoarthritis; and an IL4-IL10 fusion protein (synerkine) to control cartilage damage, inflammation, and pain in osteoarthritis (OA), haemophilic arthropathy (HA), and rheumatoid arthritis (RA)); diagnostic tools for automated analyses of radiographic joint damage and inflammation in OA, HA and RA; as well as unique animal in vivo models of osteoarthritis (rat and canine Groove model), which have all been developed over the past years.
Floris Lafeber is (co-)author of over 300 peer-reviewed papers (H-index 48), of which more than half in the top 10% of the field, supervised 30 PhD with an additional 15 scheduled. He has several patents in this field.