Dr. Feliks Kogan is an Assistant Professor in the Department of Radiology at Stanford University. He is working to develop molecularly specific imaging technologies geared toward early diagnosis of pathologies and quantitative evaluation of therapeutic efficacy in musculoskeletal disorders. In particular, he has developed and implemented several MR sequences for volumetric imaging of biochemical changes in collagen microstructure and glycosaminoglycan (GAG) content in articular cartilage, which have been shown to precede gross morphologic changes in osteoarthritis (OA). In addition, Dr. Kogan is developing molecular imaging techniques with PET to study the role of bone physiology in joint degeneration and its relationship with joint biomechanics. By combining these emerging technologies, new simultaneous PET-MRI systems present a new opportunity to study cellular and molecular mechanisms of tissue interactions in whole-joint function and degeneration.