9 September (Saturday)

• 11:30 - 12:30

  ICRS Meets Spain
• 12:45 - 14:00

  Translation of Scientific Discovery to Clinical Delivery

  • Joint Preservation Changed My Life: A Patient Journey
  • Single Stage Recycling of autologous Cartilage with MSCs
  • Development of Three-Dimensional Osteochondral Bio-Implants
  • Gene Therapy for Arthritis Has Arrived
  • Panel Discussion
• 14:15 - 14:15

  Special Sessions 1-3
  • 14:15 - 15:15

    Gene Modulation

    • Genome Sequencing Application
    • Targeted Delivery
    • Clinical translation
    • Panel Discussion
  • 14:15 - 15:15

    Navigating the Journey from Idea to Clinical Treatment

    • How do I Choose a Winning Idea?
    • Clinical Trial Design
    • Navigating the Regulatory Pathway
    • Panel Discussion
  • 14:15 - 15:15

    Biologic Matrices: The Next Frontier

    • Current Status of Additive Manufacturing
    • Hybrid Implants
    • Clinical Application
    • Panel Discussion
• 16:15 - 17:00

  Coffee Break / Exhibition / Poster Viewing
• 16:15 - 17:00

  Opening Ceremony & Awards Session
• 17:00 - 18:00

  Honorary Lectures

  • ICRS Vision Lecture
  • Clinician: "The Most 15 impactful Slides of my Career"
  • Scientist: "The Most 15 impactful Slides of my Career"
• 18:00 - 19:30

  Welcome Cocktail

10 September (Sunday)

• 06:30 - 07:00

  ICRS Fun Run for Healthy Joints
• 07:15 - 08:00

  Morning Workshops / Industry Breakfast Symposia
• 08:15 - 09:30

  Joint Preservation: Can We Change The Future?

  • Epidemiology - Can we Shift the Arthroplasty Curve?
  • Disease-Modifying or Symptom-Modifying: What should be our Goal of Treatment?
  • When is a Cartilage Defect really Osteoarthritis?
  • Challenging Treatment Paradigms with Novel Treatments
  • Panel Discussion
• 09:30 - 11:00

  Coffee Break / Exhibition / Poster Viewing
• 11:00 - 12:00

  Special Sessions 4-6
  • 11:00 - 12:00

    Big Data: Advanced Tools for the Next Discovery

    • ICRS Registry Update
    • Epidemiology/Population Health
    • Machine Learning/Artificial Intelligence
    • Panel Discussion
  • 11:00 - 12:00

    ICRS meets OARSI: Multi-omics Approach to Understanding Joint Preservation

    • Genomics/Epigenomics
    • Transcriptomics
    • Microbiomics
    • Panel Discussion
  • 11:00 - 12:00

    What are the Essential Ingredients for Successful Cartilage Repair?

    An interactive audience-based consensus debate
• 12:15 - 13:15

  Industry Sponsored Satellite Lunch Symposia 1-4
• 13:15 - 14:45

  Free Paper Sessions 1-4

  • Knee
  • Foot & Ankle
  • Shoulder
  • Hip
• 15:00 - 16:00

  Special Sessions 7-9
  • 15:00 - 15:00

    Let’s not do that again! Lessons Learned from Failures in Joint Preservation

    • Clinician Perspective
    • Scientist Perspective
    • Industry/Regulatory Perspective
    • Panel Discussion
  • 15:00 - 16:00

    What Would You Do?

    Case-Based Interactive Panel Discussion
  • 15:00 - 16:00

    Resurfacing the Entire Joint: Can we Succeed?

    • Tissue Engineering Approach with Subchondral Bone
    • Cell Approach
    • 3D Printing / Scaffolding
    • Panel Discussion
• 16:00 - 16:45

  Coffee Break / Exhibition
• 16:45 - 18:15

  Free Paper Session 5-8

  • Large Animal Studies
  • Clinical Trials
  • Allografts
  • Scaffolds
• 18:00 - 19:00

  ICRS NextGen Reception (Upon Invitation Only)
• 19:30 - 23:00

  President’s Dinner (Upon Invitation Only)

11 September (Monday)

• 07:15 - 08:00

  Morning Workshops /Industry Breakfast Symposia
• 08:15 - 09:30

  Biologics: Do we have a Consensus?

  • Are Peptides & Proteins Ready for Prime Time?
  • RP, BMC, SVF—Point of Care Options with a Track Record
  • iPS Cells: A Game Changer
  • Role of Extracellular Vesicles for Joint Preservation
  • Panel Discussion
• 09:45 - 10:45

  Special Sessions 10-12
  • 09:45 - 10:45

    Stem Cells: I want the Truth!

    • What is the Real Science?
    • Cell manufacturing and regulatory approval
    • Where will we be in 5 years?
    • Panel Discussion
  • 09:45 - 10:45

    Pharmacologic Intervention for Cartilage Repair & Joint Homeostasis

    • Cell Senescence / Aging
    • WNT Pathway
    • Industry Collaboration
    • Panel Discussion
  • 09:45 - 10:45

    Subchondral Bone: What’s New in 2023?

    • Bone Remodelling Following ACL Injury
    • Current Treatment Options for Subchondral Bone Injury
    • How to improve the Bone in OC Allografts
    • Panel Discussion
• 10:45 - 11:15

  Coffee Break / Exhibition
• 11:15 - 12:45

  Free Paper Sessions 09-12

  • Biomaterials
  • Translational OA
  • Joint Preservation
  • Small Animal Studies
• 13:00 - 14:00

  Industry Sponsored Lunch Symposia 5-8
• 14:15 - 15:45

  Free Paper Sessions 13-16

  • Stem Cells
  • Imaging
  • Rehabilitation
  • Late Breaking Clinical Trials
• 15:45 - 16:15

  Coffee Break / Exhibition
• 16:15 - 17:30

  Special Sessions 13-15
  • 16:15 - 17:30

    Imaging Methods to Assess Cartilage Repair: Was it a Success or a Failure?

    • Quantitative MRI
    • Postoperative MRI: All you need to know
    • Success or Failure? You Decide
  • 16:15 - 17:30

    Beyond Articular Cartilage: Whole Joint Preservation

    • Synovium & Cartilage — The Role of Inflammation
    • Muscle Effects on Joint Health
    • Meniscus Injury & Cartilage
    • ACL Injury & Cartilage
    • Panel Discussion
  • 16:15 - 17:30

    Joint Loading & Cartilage Health

    • How Does Mechanical Load Affect Joint Health?
    • Re-Alignment Osteotomy is the Answer!
    • Joint Distraction
    • Implantable Unloader: An Alternative to Osteotomy
    • Panel Discussion
• 17:45 - 18:45

  ICRS General Assembly (For Members Only)
• 19:30 - 23:00

  Spanish Night - Farewell Evening

12 September (Tuesday)

• 08:00 - 09:15

  State of the Art Rehabilitation after Cartilage Repair

  Latest advances in rehabilitation and return to sport
• 09:30 - 10:30

  Mini Battlefield

  • EVs are all that we need
  • No, cells will always be smarter!

   

  • Living osteochondral allograft is the gold standard
  • Cell-free and off the shelf is the new standard

   

  • We can change the natural history of an injured joint
  • All joints should meet their metal and plastic destiny

   

  • Osteotomy is all that is needed
  • No broken bones, just repair the cartilage!

   

  • Mother nature always wins with endogenous repair
  • Exogenous repair will be the answer
• 10:30 - 11:00

  Coffee Break / Exhibition
• 11:00 - 12:00

  Special Sessions 16-18
  • 11:00 - 12:00

    How Do We Measure Success in Tissue Repair? Updated Evaluation Technology

    • The next Generation of Clinical Outcome
    • Biomechanical Evaluation
    • Biochemical: The Ultimate Goal
    • Panel Discussion
  • 11:00 - 12:00

    Meniscus: State of the Art in 2023

    • Current Status of Meniscus Regeneration
    • Enhancing Meniscus Repair
    • Meniscus Transplant: Are we hitting the target?
    • Panel Discussion
  • 11:00 - 12:00

    What would you do? Case-Based Interactive Discussion

    Case presentation, audience polling, expert panel