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ISTO Technologies

ISTO Technologies

ISTO Technologies

ISTO Technologies

ISTO Technologies, Inc.
1155 Olivette Executive Parkway
Suite 200
St. Louis, Missouri 63132

Phone: +1 314 995 6049
Fax: +1 314 995 6025



STO is a unique orthobiologics company, developing breakthrough technologies that are deeply rooted in biology for spine and orthopedics.

Pioneering Orthobiologics

ISTO is a team of passionate, dedicated experts who are focused on developing breakthrough orthobiologic products that support the natural healing of the human body. Upon a firm scientific infrastructure, ISTO designs novel treatments that are successful and cost-effective, giving new hope to patients suffering from debilitating pain and loss of mobility.

What is Orthobiologics?

Orthobiologic therapies harness cells and proteins naturally found in human biology to help stimulate efficient regrowth of musculoskeletal tissues, including cartilage, bone, tendons, and ligaments.

The Building Blocks of a New Field

Orthobiologics is a rapidly advancing field that uses cell-based therapies and biomaterials to promote healing. By empowering the body to repair and regenerate itself, orthobiologic treatments offer exciting alternatives to traditional orthopedic options. Compared to the implantation of foreign hardware made of plastic and metal, orthobiologic procedures are often less invasive and more effective at restoring patients to their normal, active lives1.


In recent decades, breakthrough orthobiologic therapies have helped to improve the long-term health of patients suffering from disabling musculoskeletal disorders and injuries. The development of biological solutions for repairing cartilage andbone has given surgeons alternatives to implanting mechanical adaptations. Promising innovations in orthopedics and spinal surgeries, bone grafting, and tissue regeneration are accelerating healing, reducing hospital visits, shortening stays, and improving lives.

For nearly 20 years, ISTO has been a pioneer in the orthobiologic industry. “We’re creating groundbreaking solutions that use the beauty of human chemistry and biology,” explains ISTO Senior Director of Clinical Operations Michaela Purcell. “We’re preserving what the body was intended to do in the first place.”

ISTO’s unique orthobiologic bone growth portfolio has been adopted by many doctors and offers additional avenues of potential not yet explored. In addition, the novel cell-based therapies ISTO has in its pipeline have delivered encouraging results and confidence that they will one day revolutionize treatment continuums in spine and orthopedics. With orthobiologics, ISTO is pushing the future of medicine forward in ways that will impact millions of patients suffering from pain and disability, providing new hope for long-lasting relief and restoration.