Frank is Professor and head of the Dr. Rolf M. Schwiete Research Unit for Osteoarthritis at the Orthopaedic University Hospital in Frankfurt, Germany. Specific interests in his lab include mechanisms of skeletal development, control of cell functions in degenerative diseases and the role of the extracellular matrix (ECM). Frank studied Biology and completed his dissertation at the University of Karlsruhe, Germany. After receiving his PhD, he moved to the University of Cologne where he was working in the Center for Biochemistry. As an independent group leader he developed his own research profile focusing on pathomechanisms of chondrodysplasias and the biochemistry of the cartilage ECM. In 2010, he obtained the Venia legendi in Biochemistry and Molecular Biology from the University of Cologne. In 2016, he moved to Frankfurt and became head of a research unit dedicated to different aspects of osteoarthritis. Frank is member of the Faculty of 1000, the editorial board of the journals Cellular Signalling, American Journal of Physiology and Scientific Reports. He is member of several scientific societies and vice-president of the German Society for Matrix Biology. In 2023, he will chair the prestigious Gordon Conference on Cartilage Biology and Pathology. His research is funded by the German Research Foundation, the EU and the Dr. Rolf M. Schwiete Foundation.