Please join us in beautiful Miami Florida USA this May 2020 for our Summit conference. We will focus on Joint Preservation for our young active patients who wish to have an active lifestyle and preserve their native joints.
Review of “Allogeneic MSCs and recycled autologous Chondrons mixed in a one-stage cartilage cell transplantation: A first-in-man trial in 35 patients” from STEM CELLS by Stuart P. Atkinson
Previous studies from the laboratory of Daniel B. F. Saris (University Medical Center Utrecht, The Netherlands) reported that a novel stem cell combination represented a safe and efficient means to repair cartilage in preclinical [1] and early clinical studies [2]. Their combination strategy involves allogeneic mesenchymal stem cells (MSCs) that provide trophic support to stimulate the cartilage-producing activity of patient-derived chondrons (chondrocytes with their native matrix) isolated while preparing the damaged cartilage for repair.
This successful strategy has now progressed to the next level, and a study in STEM CELLS provides a comprehensive description of the first-in-man trial in 35 patients and an 18-month follow-up [3].
