Rosa Maria Nothnagel

DI Rosa Maria Nothnagel, PhD is a postdoctoral researcher at AC2T research GmbH and the University for Continuing Education Krems, Austria, specializing in biotribology in cartilage repair and regenerative medicine. Her interdisciplinary background in regenerative medicine and biotechnology supports research at the interface of engineering and clinical application.

Her work focuses on biotribological interactions in articulating joint systems, particularly cartilage–implant and cartilage–cartilage interfaces under physiologically relevant conditions, aiming to improve cartilage repair strategies and long-term joint function.

During her PhD, she investigated metal–cartilage interactions in partial joint arthroplasty, demonstrating that surface-engineered metal and alternative biomaterials can reduce wear and improve compatibility with native cartilage. She further developed in vitro testing strategies that replicate joint mechanics and enable more predictive preclinical assessment while reducing reliance on animal models.

She is co-inventor of a patented implant-related material concept (AT528221 B1, 2025) and author of multiple peer-reviewed publications. Current research explores advanced material systems, including biphasic designs and functional coatings based on metal–organic frameworks (MOFs) and MXenes, as a platform for future drug-loading and localized therapeutic delivery.

At the ICRS Summit 2026, she will present “What Can We Learn from Biotribology for Cartilage Research?”.